CBD and the Gut-Brain Connection: What You Need to Know About the Potential Health Benefits of CBD & THC

You must have heard that the way to a man’s heart is through his stomach, but there is nothing sexist regarding the gut-brain connection. It is an established scientific fact that our digestion system directly influences our mood, thoughts and body’s overall health. And as one of the most talked-about topics in the field of medicine at the moment, Cannabidiol, or CBD, improves our gut health and shows strong potential as a treatment for a range of diseases through its positive influences on Microbiota-Gut-Brain Axis or MGBA. In this article, we will explore what MBGA is and what science tells us about CBD’sCBD’s role in the proper functioning of the human body.

What is CBD?

We are sure many of our existing readers are already well aware of CBD. CBD oil is a non-toxic, ayurvedic blend of full-spectrum cannabis plant leaf extracts with several therapeutic properties. It contains cannabidiol and other naturally available cannabinoids in cannabis plants like CBD, CBG, THCA and Δ-9 THC. The “oil” portion of the name comes from the fact that it is usually mixed with a carrier oil like coconut or hemp seed oil to make it more easily ingestible. For example, at CannaBlithe, we use medium-chain triglycerides (MCT) oil (for example, virgin coconut oil) in our CBD products for allied health benefits. Our full-spectrum CBD oil offers the holistic advantage of essential cannabinoids and flavonoids present in CBD as they work together synergistically to promote healing. Indian ayurvedic scriptures have mentioned various usage of cannabis leaf extracts. Our Vaidyas (traditional Ayurveda practitioners) recommend cannabis extract-based natural medicines (e.g., bhang churna) for treating nerve pain, irregular digestion, diarrhea, piles, sleeplessness and other conditions.To understand the effects of cannabidiol and other available cannabinoids in CannaBlithe’s medicine-grade CBD oil on the human body and health, we need to understand the Endocannabinoid system (ECS).

CBD and the Endocannabinoid System

One of the important cannabinoid relationships in the human body is the link to the endocannabinoid system. This system consists of receptors CB1 & CB2, which are located throughout the body through our central nervous system. When CBD AND THC bind to these receptors, our endocannabinoid system responds by activating specific proteins (such as those inhibiting body pain). While CBD does not bind to the same receptors as THC, research has shown that it acts on its own set of receptors and has different biological effects. Studies show that CBD has anti-inflammatory properties and can inhibit pain by activating the endocannabinoid system. It is the reason some people use it to treat various diseases, including chronic pain and inflammation, as well as epileptic seizures.

Benefits of CBD in Gut-brain axis and overall human Health

The benefits of CBD in human health are numerous. CBD can be used as an anti-inflammatory, analgesic, and anti-cancer agent; it has anti-seizure, antipsychotic and anti-anxiety properties. Most intriguing, studies have shown that CBD has strong potential as a treatment for various inflammatory conditions such as multiple sclerosis, rheumatoid arthritis, and even alcohol use disorder (AUD).

Indeed, medical research around CBD’s impact on human health is still an evolving field of study. Most CBD benefits are attributed to the ECS mechanism and MGBA (commonly known as a gut-brain connection). We have already learned how cannabidiol and other naturally-extracted cannabinoids influence the central nervous system; MGBA, or gut-brain axis is the biochemical signaling that takes place between our GI (digestive) tract and central nervous system (CNS).

Cannabidiol and other common cannabinoids influence the gut-brain axis in multiple ways. Some of the significant impacts are,

  • Reducing intestinal permeability
  • Promoting the growth of healthy gut microbiota
  • Containing intestinal inflammation
  • Improving digestion mechanism

Improved digestion helps us assimilate micronutrients, minerals and other healthy organic molecules from the food we intake. It strengthens cells’ immunity against diseases and harmful microbes.


CBD is one of the many cannabinoids present in the cannabis plant. It is a non-psychoactive compound with many health benefits; it can be consumed directly (sublingually) through food, beverages, supplements, or topically. CannaBlithe is reputed for its ethically-sourced, third-party accredited lab-tested, organic CBD oil and other CBD-infused products. We have a legally-approved CBD dispensation mechanism in which CBD oil is accessible  (delivered at the doorstep) against a valid prescription. So, consult with your doctors or with our panel of medical professionals before starting CBD-based treatment of specific health conditions.

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